Is It a Carcinoma or a Lymphoma? |
||
| Sections Clinical History Light Microscopy Flow Cytometry Electron Microscopy Diagnosis Discussion Readers' Comments Reader Feedback |
Electron Microscopy |
|
| Tissue was retrieved from a paraffin block, deparaffinized and the deparaffinized tissue was processed for electron microscopy. | ||
|
The nuclei of the neoplastic cells have round profiles. There is a central, electron dense nucleolus. The heterochromatin is dispersed in central and peripheral clumps. | |
 Figure 6. Magnify Image |
Electron dense mitochondria, rough endoplasmic reticulum and polyribosomes are present in the cytoplasm of the malignant cells. Cell membranes are closely apposed. Rare, filopodia project into the intercellular spaces. | |
 Figure 7. Magnify Image |
Sparse, primitive intercellular junctions are present along cell membranes. | |
| Diagnosis | ||
| February 1988 Case-of-the-Month | ||
