COTM 1997. Case 1 - Electron Microscopy

May 1, 1997

Electron Microscopy of Paraffin Embedded Tissue

Case 1 - Clinical History

Light Microscopy

Electron Microscopy

Fig 1. Uranyl Acetate Lead Citrate
Original Mag 9,600 X
A Langerhan's cell (LC) is surrounded by eosinophils (E) and collagen (C).

Fig 2. Lead Citrate Uranyl Acetate
Original Mag 38,000
Several, long, Birbeck Granules (arrow) are present in the peripheral cytoplasm of the Langerhan's cell. Other organelles include mitochondria (M) and lysosomes (L). A portion of the Langerhan's cell nucleus (NUC) and extracellular collagen are also present.

Case 2 - Clinical History

Case 3 - Clinical History

	Fig 1. Uranyl Acetate Lead Citrate Original Mag 9,600 X A Langerhan's cell (LC) is surrounded by eosinophils (E) and collagen (C).

	Fig 2. Lead Citrate Uranyl Acetate Original Mag 38,000 Several, long, Birbeck Granules (arrow) are present in the peripheral cytoplasm of the Langerhan's cell. Other organelles include mitochondria (M) and lysosomes (L). A portion of the Langerhan's cell nucleus (NUC) and extracellular collagen are also present.