Figure
2.
Figure
2.
Micrograph of normal human skin: A basal keratinocyte attached
to the basal lamina with many hemidesmosomes. Note the following
structures in the basement membrane complex. (mag. X43,000) Hemidesmosomes
- White arrow; Sub-basal dense plaque - Arrow head; Anchoring
filaments- *; Lamina Lucida - LL; Basal Lamina - BL; Anchoring
Fibrils- AF; Collagen in papillary dermis - C.
Figure 3.
The anchoring fibrils are present with a normal morphology on the dermal side of the lamina densa.
Figure 4 
Figure 5.
In both Figure 4 (bullous area) and Figure 5 (nonbullous area), there is abnormal morphology of the hemidesmosomes attaching the keratinocytes to the lamina densa. There is total absence of the sub-basal dense plaques of the hemidesmosomes of the basal keratinocytes. (Mags. X55,000)
